Healthcare
Large and Small Scale Bioprocessing Market Size to Grow at a CAGR of 6.2% During the Forecast Period 2021-2026
Large and Small Scale Bioprocessing Market Overview
Large and Small Scale Bioprocessing Market size was estimated at $30.32 billion in 2020, projected to grow at a CAGR of 6.2% during the forecast period 2021-2026. Large and Small Scale Bioprocessing industry has witnessed huge demand over the last decade owing to biopharmaceuticals need. Bioprocess or fermentation is a major component of old and modern biotechnology methods and usually involve entire living cells, organelles, or enzymes as a biocatalyst, and aims to bring about some chemical or physical improvements of the biochemical material extracted from the medium.
Ultrafiltration (UF) is an operation unit which separates large solutes from small solutes and solvents. Excipients are inert pharmaceutical ingredients used in the formulation of products. Excipients are important and play a vital role in the drug development process, as well as the formulation and administration of stable dosage forms. According to European Pharmaceutical Review, Epileptic patients in Australia in the late 1960s who were taking phenytoin capsules suffered extreme intoxication as a result of a poor excipient option.
Thin porous rigid UF membranes are used in UF as flat sheets or tubes. These separate solutes by holding and moving them based on their size and, secondarily, by charge or other fields acting on the solute-surface interaction.
Key Takeaways
- Based on geography, North America Large and Small Scale Bioprocessing Market held the largest revenue share of 38% in 2020 attributed to the high disposable income in the region and rise in demand for biopharmaceuticals.
- Significant upsurge in the R&D initiatives by the major players in various regions coupled with the government initiatives are driving the market.
- In the coming years, biopharmaceuticals production is projected to be a lucrative source of revenue for the pharmaceutical industry. Nano-biocatalysts, for example, were developed to increase turnaround times by increasing enzyme activity and stability, thus increasing bioproduction.
Large and Small Scale Bioprocessing Market: Market Share (%) by Region, 2020
For more details on this report - Request for Sample
Large and Small Scale Bioprocessing Market Segment Analysis – By Product Based on Product, Large and Small Scale Bioprocessing Market is segmented into Fermenters /Bioreactors, Cell Culture Products, Bioreactors Accessories, Filtration Assemblies, Bags & Containers. Fermenters/Bioreactors segment held the majority of revenue market share in 2020 attributed to the high consumption rate and large-scale bioproduction requirements from major industry participants. Automated cell culturing with specialized bioreactor designs is critical for the production of value-added goods, aids the segment's growth. Large-scale fermentations are used to produce large amounts of ethanol, which is used in the manufacture of food, alcohol, and even gasoline. The availability of the diversified range of bioreactors on the basis of size, operation mode, fluid flow type, applications, and usage type are projected to propel revenue of the segment in the upcoming years. Cell culture products segment is poised to grow with the fastest CAGR of 6.6% in the forecast period 2021-2026 owing to ongoing advances in cell line growth, such as the development of recombinant cell lines. The production of biopharmaceutical-derived cell lines from mammalian cell lines is expected to boost this segment's development. Large and Small Scale Bioprocessing Market Segment Analysis – By Type: Based on Type, Large and Small Scale Bioprocessing market is segmented into Small Scale, Industrial Scale. Industrial Scale segment held the highest revenue market share in 2020. The growth in the market is mainly attributed to the market's constant implementation of techniques and tools to help industrial-scale bioprocessing increased the adoption of industrial-scale bioprocessing. For example, GE Healthcare launched Capto Q XP chromatography resin in June 2016. These chromatography resins are powerful anion exchangers that are used in the industrial purification of large-scale biomolecules. These measures are anticipated to positively impact the segment's growth in the forecast time-frame. Batch fermentations, fed-batch operations, and continuous cultures are all options for industrial fermentations. Continuous fermentations are uncommon, compared to batch and fed-batch operations. Excipients in pharmaceuticals are simply something that isn't the active pharmaceutical ingredient. Small Scale segment is expected to witness the fastest CAGR of 6.9% in the forecast period 2021-2026. As part of upstream processing, small scale bioreactors provide parallel processing and enable the evaluation of a series of experiments for bioprocess optimization. This factor is projected to support small-scale bioprocessing's projected development. Large and Small Scale Bioprocessing Market Segment Analysis – By Geography: On the basis of Geography, North America Large and Small Scale Bioprocessing Market held 38% of revenue share in 2020. This is majorly attributed to the technological advancement and cutting-edge biomanufacturing R&D. Other important factors affecting the market's success in this area include developed infrastructure and growing funds for bioprocessing technology. Furthermore, the large share of this segment can be attributed to the existence of a large number of biomanufacturing facilities in this area. Asia-Pacific market is forecast to rise with the fastest CAGR for the period 2021-2026. Several companies in the area are outsourcing biologics manufacturing and clinical trials, and it is a key factor driving development in this sector. Other facilities are beginning to establish manufacturing strategies for GMP production for key markets, with capability involving commercial-scale stainless steel and single-use bioreactors, while new facility construction and expansions represent the demand for biologics for domestic consumption. Large and Small Scale Bioprocessing Market Segment Analysis-Drivers Increasing Funding by the Governments: The market is also expected to expand as funding and investments to support the production and study of new biopharmaceuticals expand. The Indian government, for example, initiated a National Biopharmaceutical Mission in 2017. The government has invested US $250 million in the initiative, which includes a US$ 125 million loan from the World Bank, to facilitate the production of biological drugs in India. The Johns Hopkins University School of Medicine (JHUSM) teamed up with the University of Liverpool in the year 2017 for creating novel nanomedicine methods for the HIV therapy. Also, they secured a grant of $3 million from the National Institutes of Health (NIH) for development of enduring R&D and new technologies. Large and Small Scale Bioprocessing Market Segment Analysis-Challenges Single Use Bioreactors/Fermenters: Single-use bioreactors are often made of plastic derivatives. In addition to concerns about possible leachable and extractable materials, routine large-scale disposal of such plastic reactors is also a concern for the environment. Furthermore, the reactor bag's insulating plastic material prevents efficient heat transfer, reducing the thermal jacket's impact. Film-related threats, unit management risks, operation risks, and supply chain risks are all major risks associated with single-use technology. As a result, it's difficult for biopharmaceutical companies to trust the integration of single-use technologies into bioprocessing process steps and applications. The industry had seen evidence that a single bag failure could cost a company between $100,000 and $1 million, and that leaks in single-use systems could cost a company up to $20 million per year. Large and Small Scale Bioprocessing Market Segment Landscape: Product launches, mergers and acquisitions, joint ventures and geographical expansions are key strategies adopted by players in the Large and Small Scale Bioprocessing Market. Large and Small Scale Bioprocessing Market top 10 companies are Thermo Fisher Scientific Inc., Applikon Biotechnology, Merck KGaA, Samsung Biologics, Eppendorf AG, Lonza, PBS Biotech Inc, Binex Co. Ltd, Finesse, CellGenix GmbH Meissner Filtration Products Inc., Developments:- In June 2019, MabPlex has announced opening of its subsidiary in Zhangjiang (Hub of Dozens of biotech companies), Shangai in order to serve process development outsourcing needs.
- In May 2019, WuXi Biologics has announced to construct a new 1.3million sq. ft manufacturing facility center for the innovative biologics in Chengdu.
