Rising Public Awareness to Propel the Protein Chip Market
A miniaturized 2D array, which allows performing simultaneously high throughput studies of thousands of proteins and subsequently the analysis of thousands of parameters within a single experiment are referred to as Protein microarrays or chips. The number of therapeutic antibodies and recombinant proteins developed has risen dramatically over the past decade. The micro array format has become the leading technology that enables fast, easy and parallel detection of thousands of addressable elements and side-by-side measurements. Recent progress in the field of protein chips, include surface chemistry, capture molecule attachment, protein labeling and detection methods, high-throughput protein/antibody production, and applications to analyze protein families and entire proteomes.
Protein microarrays, an emerging class of proteomic technologies, are becoming critical tools in biochemistry and molecular biology. Two classes of protein microarrays are currently available: analytical and functional protein microarrays. Antibody arrays can be used for clinical diagnosis or environmental/food safety analysis. Functional protein arrays are mainly used to study various types of protein activities, including protein-protein, protein-lipid, protein-DNA, protein-drug, and protein-peptide interactions, to identify enzyme substrates and to profile immune responses. Protein microarray technology has been shown to be a useful tool for multiplexed detection and proteomics studies.
Increasing awareness and knowledge of public and medical professional about available protein chip technology is crucial for the applications like diagnostics, proteomics, protein Functional Analysis and antibody Characterization. Awareness efforts have led to the rise in protein analysis procedures, digital bioassay usage and some others in recent years. Activities include Improvements in generating large sets of antibody reagents, recombinant proteins from a variety of host cells and other types of capture molecule will further increase the interest in this field. The protein micro arrays are also used in the development of antigen-specific therapies for autoimmunity, cancer and allergies; the identification of small molecule targets that could potentially be used as new drugs.
